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Schizophrenia affects approximately one in every hundred people. One of the major hurdles we cleared in modern understanding is the recognition that it is a brain disease. It was previously believed that schizophrenia had an inexorable downhill course, although now we know that, with treatment, some patients can regain functioning in certain areas. Unfortunately 10 to 30% of people with schizophrenia do not respond adequately to standard treatments. A major aim of my research is to develop new treatments for this minority.

Owen M. Wolkowitz, M.D. Psychiatrist, Researcher